FLT3基因突变,second tyrosine kinase domain
1)second tyrosine kinase domainFLT3基因突变
1.This study was aimed to investigate the frequency of FMS-like tyrosine kinase 3(FLT3) mutations including internal tandem duplication(ITD) mutation of juxtamembrane region and point mutation of thesecond tyrosine kinase domain(TKD) in acute myeloid leukemia(AML) patients and its clinical significance.结论:FLT3基因突变是AML患者中常见的突变,FLT3-ITD突变较FLT3-TKD点突变发生率高,FLT3-ITD有突变的AML患者预后差;FLT3-TKD点突变对预后的影响不明显。
英文短句/例句
1.FMS-like Tyrosine Kinase 3 Gene Mutations in Acute Myeloid Leukemia急性髓系白血病FLT3基因突变研究
2.Detection of FLT3 Gene Mutation in Malignant Hematopoietic Patients and Its Clinical Significance;恶性血液病FLT3基因突变的检测及临床意义
3.Study of FLT3 Gene Mutations in Patients with Acute Promyelocytic Leukemia;急性早幼粒细胞白血病患者FLT3基因突变的研究
4.The Expression of SSBP2 Gene and Detection of FLT3 Gene Mutation in Acute Myeloid Leukemia Patients;急性髓系白血病患者SSBP2基因表达分析及FLT3基因突变检测
5.Mutations and Expression of FMS-Like Tyrosine Kinase 3 Gene in Patients with Acute Promyelocytic Leukemia and Its Clinical Significance;急性早幼粒细胞白血病患者FLT3基因突变与表达及其临床意义
6.FLT3 Mutation in Patients with Acute Lymphoblastic Leukemia and Its Clinical Significance急性淋巴细胞白血病FLT3基因突变的发现及临床意义
7.The detection of FLT3 and FLT3/ITD gene mutation by polymerasechain reaction single-strand conformation polymophism in acute myeloid leukemia patientsPCR-SSCP检测急性髓系白血病患者FLT3基因及FLT3/ITD基因突变
8.Study of FLT3 and DCK Gene Mutations in Acute Leukemia by Denaturing HPLC;应用变性高效液相色谱方法研究急性白血病FLT3、DCK基因突变
9.Prevalence and Clinical Significance of FLT3 Internal Tandem Duplication Mutation in Elderly Acute Myeloid Leukemia老年急性髓细胞白血病FLT3-ITD基因突变检测及临床研究
10.Research of NPM1 and FLT3-ITD Gene Mutations in Adult Patients with Acute Myeloid Leukemia成人急性髓细胞白血病NPM1与FLT3-ITD基因突变的研究
11.Detection and clinical significance of FLT3 internal tandem duplication mutation in acute myeloid leukemia急性髓细胞白血病FLT3-ITD基因突变的检测及其临床意义
12.The Clinical Prevelence of FLT3 Mutations in Acute Leukemia;FLT3突变在急性白血病中的临床意义
13.Research of FLT3/ITD Mutation in Acute Myelocytic Leukemia;急性髓细胞白血病FLT3/ITD突变的研究
14.Gene cloning, expression and purification of Human FLT3 Ligand;人FLT3 Ligand基因的克隆、表达与产物纯化
15.A Study of Flt3 Gene Expression and Its Significance in Acute Leukemia;Flt3基因在急性白血病中的表达及其意义的研究
16.RNAi-induced Inhibition of FLT3 Expression and Induction of Apoptosis in HL-60 Cells;RNAi抑制HL-60细胞FLT3基因表达及诱导凋亡的研究
17.FLT3 Length Mutations, FLT3 Expression and Their Clinical Implications in Patients with Myeloid Leukemia;FLT3长度突变及表达水平在急性髓系白血病中的临床意义
18.Expression of FLT3 Internal Tandem Duplication in Pediatric Patients with Acute Myeloid Leukemia and Its Correlation with Multidrug ResistanceFLT3-ITD突变在儿童急性髓性白血病中的表达及其与多药耐药的关系
相关短句/例句
FLT3/ITD mutationFLT3/ITD基因突变
1.The value detection of FLT3 gene andFLT3/ITD mutation in myelodysplastic syndromes;骨髓增生异常综合征患者FLT3基因及FLT3/ITD基因突变的检测及价值
2.Results The expression of FL T3 gene were detected in 43 AML patients with agarose gel and single-strand conformation polymorphism eletrophoresis;There was noFLT3/ITD mutation with agarose gel eletrophoresis,butFLT3/ITD mutation was detected in 15 cases(35%)with single-strand conformation polymorphism gel eletrophoresis.方法采用多聚酶链反应(PCR)联合单链构象多态性(SSCP)方法检测43例不同免疫分型AML患者DNA水平FLT3基因及FLT3/ITD基因突变。
3)FLT_3 mutationsFLT3突变
1.Objective:To investigate theFLT_3 mutations in leukemia patients by peripheral blood and indicate the relationship betweenFLT_3 mutations and the pathogenesis of leukemia.结论Flt3基因突变和白血病发生、发展相关,外周血可以替代骨髓检测FLT3突变;FLT3-ITD阳性患者化疗缓解率低、易复发、预后差;外显子14、L567突变点是否为FLT3一个新的突变热点需进一步研究。
4)FLT3-ITD mutationFLT3-ITD突变
5)FLT3 geneFLT3基因
1.The value detection ofFLT3 gene and FLT3/ITD mutation in myelodysplastic syndromes;骨髓增生异常综合征患者FLT3基因及FLT3/ITD基因突变的检测及价值
2.This study was aimed to explore the role ofFLT3 gene in AML pathogenesis and its significanse for detection of MRD.本研究旨在探讨FLT3基因在AML发病中的作用及对微小残留病(MRD)检测的意义。
6)Flt3-LgeneFlt3-L基因
延伸阅读
[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]分子式：C16H16ClN3O3S分子量：365.5CAS号：26807-65-8性质：暂无制备方法：暂无用途：用于轻、中度原发性高血压。
