散发性结直肠癌,Sporadic colorectal cancer
1)Sporadic colorectal cancer散发性结直肠癌
1.Refinement of High Heterozygosity Loss on Chromosome in Sporadic Colorectal Cancer;散发性结直肠癌高频杂合缺失精细定位及SMAD4基因突变的初步研究
2.Objectives To explore the mechanism of DPC4 gene in Chinese sporadic colorectal cancer.目的分析我国散发性结直肠癌肿瘤组织中,DPC4/SMAD4基因杂合性缺失的发生情况。
3.Objective:(1)To observe β -Catenin gene aberrant expression and mutation in sporadic colorectal cancers(SCRC) and explore its clinicopathological correlation.目的：(1)观察β-Catenin基因在散发性结直肠癌(SCRC)中胞浆胞核异常表达特征及突变发生率并探讨其临床病理相关性；(2)检测SCRC标本的微卫星不稳定(MSI)状态，分析其与β-Catenin基因突变的关系；(3)检测SCRC组织及癌旁正常粘膜中β-Catenin mRNA的含量，探讨其与SCRC中的β-Catenin蛋白异常表达以及临床病理学指标间的关系；(4)检测SCRC单细胞的拉曼光谱，以便建立区分癌细胞和正常细胞的诊断识别模型并分析生化改变。
英文短句/例句
1.Relationship of Expression of hMSH2 and PTEN in Sporadic Colorectal Carcinoma;散发性结直肠癌中hMSH2与PTEN表达相关性研究
2.The Study on Methylation of hMLH1 Gene in Sporadic Colorectal Cancer;散发性结直肠癌中hMLH_1启动子甲基化的研究
3.The Basal Study of Protein Expression of XRCC1 and MGMT in Sporadic Colorectal Carcinoma;XRCC1、MGMT在散发性结直肠癌中表达的基础研究
4.The Expression and Correlation between CD4, CD8 and MSI in Sporadic Colorectal Carcinoma;散发性结直肠癌CD4、CD8表达与MSI关系的研究
5.Study of Detection Strategy for Sporadic Colorectal Carcinoma with the Mutator Phenotype;具有突变子表型散发性结直肠癌筛选策略研究
6.Mitochondrial Genome Instability in Sporadic Colorectal Cancer散发性结直肠癌线粒体基因组不稳定的研究
7.Study of hMSH2 Gene Mutation in Guangxi Spordic Colorectal Cancer广西散发性结直肠癌中hMSH2基因突变研究
8.The Research of hMLH1 Gene Mutation of Colorental Cancer in Guangxi广西散发性结直肠癌错配修复基因hMLH1突变研究
9.Mutations in APC,K-ras,p53 and MMR gene in colorectal cancer散发性结直肠癌APC、K-ras、p53、MMR基因突变检测
10.Mapping and Analysis of Methylation Status of hMLH1 Promoter in Human Sporadic Colorectal Carcinoma散发性结直肠癌中hMLH1基因甲基化的实验研究
11.The Relationship between Loss of Heterozygosity of FHIT Gene and Microsatellite Instability in Sporadic Colorectal Cancer散发性结直肠癌FHIT基因杂合性缺失与微卫星不稳定性的关系
12.Association between survivin promoter -31C/G polymorphism and genetic susceptibility to sporadic colorectal cancersurvivin基因启动子区-31C/G多态性与散发性结直肠癌遗传易感性的关系
13.Significance of Secreted Frizzled-Related Protein in the Process of Tumorigenesis in Human Sporadic Colorectal Carcinomas分泌型卷曲相关蛋白在散发性结直肠癌发生中的作用
14.Expression, Mutation and LOH of Gene ING1 in Sporadic Colorectal Carcinoma;散发性结直肠癌中ING1基因的表达、突变及杂合性缺失研究
15.Studies on β-Catenin Mutation and Aberrant Expression in Sporadic Colorectal Cancers and Raman Spectra of Single Optically Trapped Sporadic Colorectal Cancer Cells;散发性结直肠癌的β-Catenin基因突变及表达和单细胞拉曼光谱研究
16.Expression, Mutation, and Methylation of P33～(ING1b) in Sporadic Colorectal Carcinoma;散发性结直肠癌中P33～（ING1b）的表达、突变及甲基化研究
17.Refined Deletion Mapping of Loss of Heterozygosity in Sporadic Colorectal Cancer;散发性结直肠癌等位基因杂合缺失的精细定位研究
18.Refinement of High Heterozygosity Loss on Chromosome in Sporadic Colorectal Cancer;散发性结直肠癌高频杂合缺失精细定位及SMAD4基因突变的初步研究
相关短句/例句
sporadic colorectal carcinoma散发性结直肠癌
1.Mapping and analysis of the methylation variable positions profiles of hMLH1 promoter CpG islands in humansporadic colorectal carcinoma;散发性结直肠癌中hMLH1基因启动子区CpG岛MVPs图谱的绘制与分析
3)sporadic rectal cancer散发性直肠癌
1.Objective To evaluate the relationship of MSI expression and clinical-pathological parameters in the prognosis ofsporadic rectal cancer.目的探讨散发性直肠癌临床、病理特征与微卫星不稳定性(Microsatellite instability,MSI)表达之间的关系。
2.Objective To investigate the prevalence of microsatellite instability (MSI) and the relationship with the clinicopathological characteristics insporadic rectal cancer of Chinese Han population.目的探索中国汉族人散发性直肠癌的微卫星不稳定的频率，并探讨其与临床病理学特征的关系。
4)Metastatic colorectal cancer转移性结直肠癌
1.The transient CEA elevation induced by chemotherapy in patients with metastatic colorectal cancer;转移性结直肠癌患者化疗后血清癌胚抗原水平的变化
2.Irinotecan plus 5-FU/LV in line 2 treatment for metastatic colorectal cancer;伊立替康联合氟尿嘧啶/亚叶酸钙二线治疗转移性结直肠癌
3.New drug for metastatic colorectal cancer treatment——cetuximab;治疗转移性结直肠癌新药——西妥昔单抗
5)obstructive colorectal cancer梗阻性结直肠癌
6)Sporadic colorectal cancer散发性大肠癌
1.Study on significance of single nucleotide polymorphisms in the redox domain of aprimidinic/apurinic endonuclease/redox factor-1 gene in Chinese sporadic colorectal cancer;脱嘌呤/嘧啶核酸内切酶基因氧化还原功能区单核苷酸多态性在散发性大肠癌中存在意义的探讨
2.Correlation between patient′s age at onset of sporadic colorectal cancer and microsatellite instability in cancer tissues;错配修复基因变异与中国人散发性大肠癌发病年龄之间的关系
延伸阅读
肛管直肠癌gangguan zhichang’ai肛管直肠癌carcinoma of anus and rectum发生于肛管直肠的恶性肿瘤。病至后期肛门狭窄，犹如锁住一样，故又称锁肛痔。清代《外科大成》对本病有较详细的描述。多由于忧思抑郁,以致气机逆乱,血浊瘀凝，湿热邪毒蕴结于下；或由于嗜酒暴食，过食膏粱厚味，久泻久痢等诱发。临床上发现部分直肠息肉可转变为癌。例如中国南方地区的血吸虫卵沉积直肠壁形成肉芽肿发生的癌变，以及慢性溃疡性结肠炎、病毒性淋巴肉芽肿发生的癌变；肛口疤痕组织、湿疣、痔、瘘等，日久亦有癌变者。本病早期症状轻微，常被忽视。排便习惯改变，排便次数增多或便意频繁以及一种虚无的便意感，常被认为是早期症状。中期大便带有脓血和粘液，有特殊臭味，里急后重，易被误诊为痔疮及菌痢，大便形状变细、变扁、排便困难或便前腹痛腹胀。及至恶液质、转移症状等出现，则属癌肿后期。本病一经确诊，就应及早手术治疗。中药能扶持正气，增强和提高机体抗病力、免疫力，抑制癌肿的发展，故无论术前术后均为良好的治疗手段，尤其在化疗、放疗中应用，可减轻和消除副反应。临床上常采用扶正祛邪、清热解毒、活血攻坚、除痰散结等治法方药。（唐汉钧）
