酪氨酸激酶B,TrkB
1)TrkB酪氨酸激酶B
1.Objective To investigate expression of brain-derived neurotrophic factor(BDNF)TrkB andTrkB mRNA in cerebral cortex and hippocampus in bilirubin-induced encephalopathy by establishing an experimental model and to explore their roles and mechanism of action so as to provide a new approach for treatment of the disease.目的通过实验观察胆红素脑病时脑源性神经营养因子的特异性受体酪氨酸激酶B及酪氨酸激酶B信使RNA在大脑皮层及海马的表达,探讨其在胆红素脑病中可能的作用及机制,为新生儿胆红素脑病新的治疗途径提供实验依据。
2.Objective:The experiment will study the learning and memory ability of AD rats and the quantity of BDNF、TrkB and CREB in order to study the therapeutically effect and mechanism of the electroacupuncture(EA) on Alzheimer disease(AD), which will offer experimental basis of applying EA in clinic practice of the acupuncture-moxibustion.目的:通过研究电针风府穴对AD大鼠学习记忆能力、脑源性神经营养因子(Brain-derivedneurotrophiefactor,BDNF)及其受体酪氨酸激酶B(Tyrosinekinase-B,TrkB)阳性神经元数量、cAMP反应元件结合蛋白(cAMP responsive element binding protein,CREB)阳性神经元数量的影响,探讨电针风府穴对AD治疗作用及其作用机理,为针灸临床提供实验依据。
英文短句/例句
1.Expressions and Significance of BDNF and TrkB in Salivary Adenoid Cystic Carcinoma;涎腺腺样囊性癌中脑源性神经营养因子及酪氨酸激酶B的表达及意义
2.Experimental Studies on Rat Bone Marrow Stromal Cells Modified with Protein-tyrosine Kinase Receptor B Gene;蛋白酪氨酸激酶受体B基因修饰骨髓基质细胞的实验研究
3.Preliminary Research of RAI16 Protein Interacting with Tec Tyrosine Kinase;Tec酪氨酸激酶作用蛋白RAI16的初步研究
4.Expression of receptor tyrosine kinase EphA1 in gastric cancer and its clinicopathological significance受体酪氨酸激酶EphA1 mRNA在胃癌中的表达
5.Detection of TrkB and BDNF gene expression in nasopharyngeal carcinoma by real-time RT-PCR酪氨酸激酶受体B与脑源性神经营养因子mRNA在鼻咽癌中的定量表达
6.The name is soluble f-m-s-like tyrosine kinase one?这种蛋白质叫做可溶解fms样酪氨酸激酶一，
7.The Research of Antibody Against Muscle-specific Tyrosine Kinase in Myasthenia Gravis among Chinese;重症肌无力患者酪氨酸激酶抗体的相关研究
8.Tec Tyrosine Protein Kinase Involved in Multidrug Resistance of Hepatocelluar Carcinoma;Tec酪氨酸蛋白激酶参与肝癌多药耐药的研究
9.c-Abl Stabilizes Estrogen Receptor by Phosphorylation and Regulates Its Transcription Activity;c-Abl非受体酪氨酸激酶调节ERα转录活性的研究
10.Study on the Prevalence of Protein Tyrosine Kinase JAK2V617F Mutation in the Western Population;西方人群中蛋白质酪氨酸激酶JAK2~（V617F）突变率研究
11.Expression and Clinical Significance of Receptor Tyrosine Kinase RON in Lung Carcinoma肺癌组织中酪氨酸激酶受体RON的表达及意义
12.Molecular targeted therapies:targeting receptor tyrosine kinases in the treatment of gastric cancer靶向于受体酪氨酸激酶的胃癌分子靶向治疗
13.Tyrosine Kinase Mutation and Acute Myeloid Leukemia with t(8;21)酪氨酸激酶突变与t(8;2急性髓系白血病
14.Advances in the inhibitors of FLT-3 receptor tyrosine kinaseFLT-3受体酪氨酸激酶抑制剂的研究进展
15.Multi-targeted protein tyrosine kinase inhibitor:research advances多靶点蛋白酪氨酸激酶抑制剂的研究进展
16.Advances in the research of multi-target tyrosine kinase inhibitors多靶点抗肿瘤酪氨酸激酶抑制剂的研究开发
17.Expression of receptor tyrosine kinase EphA7 in gastric carcinoma and its clinical significances受体酪氨酸激酶EphA7基因在胃癌中的表达及意义
18.Effect of Receptor Protein-tyrosine Kinases in Tumor Angiogenesis受体酪氨酸激酶在肿瘤血管新生中的作用
相关短句/例句
Tyrosine kinase B酪氨酸激酶B
1.Tyrosine kinase B expression correlates with perineural invasion in salivary adenoid cystic carcinoma.;酪氨酸激酶B在涎腺腺样囊性癌中的表达及与嗜神经侵袭的关系
2.Objective:To investigate the relationship of the expression of brain-derived neurotrophic factor(BDNF) and tyrosine kinase B(TrkB) to salivary adenoid cystic carcinoma(SACC).目的:探讨脑源性神经营养因子(brain-derived neurotrophic factor,BDNF)及其受体酪氨酸激酶B(tyrosine kinase B,TrkB)与涎腺腺样囊性癌(salivary adenoid cystic carcinoma,SACC)的关系。
3)TrkB酪氨酸激酶受体B
1.The Expression of BDNF andTrkB in Rat Cerebellum;脑源性神经营养因子及酪氨酸激酶受体B在大鼠小脑的表达
2.Background and purpose:TrkB, a neurotrophic tyrosine kinase receptor,serves as a potent and specific suppressor of anoikis of non-malignant epithelial cells, and confers high metastatic capacity to these cells.背景与目的:失巢凋亡抑制因子酪氨酸激酶受体B(tyrosine kinase receptor, TrkB)能诱导正常上皮细胞的恶性转化并且使该细胞具有高转移能力。
3.Background and purpose:TrkB,a neurotrophic tyrosine kinase receptor,serves as a potent and specific suppressor of anoikis of non-malignant epithelial cells,and induces high invasion capacity in these cells.背景与目的:失巢凋亡抑制因子酪氨酸激酶受体B(tyrosine kinase receptor,TrkB)能诱导正常上皮细胞的恶性转化并且使该细胞具有高侵袭能力。
4)Tyrosine kinase receptor B酪氨酸蛋白激酶受体B
1.Expression of tyrosine kinase receptor B in human follicle;酪氨酸蛋白激酶受体B在人卵泡中的表达及意义
2.BDNF initiate its biological effects by bounding to tyrosine kinase receptor B (TrkB) on the cell membrane.目的：关于人卵泡液中存在着由卵丘颗粒细胞分泌的脑源性神经营养因子(BDNF)的报道提示：人卵巢中可能有BDNF赖以发挥其生物学效应的特异性高亲合力受体—酪氨酸蛋白激酶受体B(TrkB)的存在。
5)trkB酪氨酸蛋白激酶B
6)TrkB酪氨酸激酶B受体
1.Study on the Expression of BDNF andTrkB in Rat Hippocampal Formation CA1;脑源性神经营养因子及酪氨酸激酶B受体在大鼠海马结构CA_1区的表达研究
延伸阅读
酪氨酸蛋白激酶抑制剂分子式：CAS号：性质：一类能抑制蛋白质酪氨酸激酶活性的化合物。酪氨酸蛋白激酶能特异性地将磷酸根转移到蛋白质的酪氨酸残基上使其磷酸化，是许多配体活化的生长因子受体和一些癌基因产物，在肿瘤组织中含量高。酪氨酸蛋白激酶抑制剂可作为ATP与酪氨酸蛋白激酶结合的竞争性抑制剂，也可作为酪氨酸的类似物阻断表皮生长因子受体的肽位点和酪氨酸蛋白激酶的编码，抑制细胞增殖，可望开发为抗肿瘤药物，但对完整细胞没有表现出选择性。
