what I said to him he refused to follow my advice.A. Regardless ofB. Assuming thatC. In

问题补充：

what I said to him, he refused to follow my advice.

A. Regardless of

B. Assuming that

C. In vain

D. Even though

答案：

(答案→)A. Regardless of

B. Assuming that

C. In vain

D. Even though

解析：本题的含义是不管我对他说了什么，他都拒绝采取我的建议，regardless of表示不管的意思，故本题选A。