问题补充：
---
---I have a headache.
A. What wrong with you?
B. How is it?
C. What’s the matter?
D. What’s your question?
答案：
A. What wrong with you?
B. How is it?
(答案→)C. What’s the matter?
D. What’s your question?
解析：句意：--你怎么了？--我头痛。分析：当询问对方怎么了，常用的语句为：What’s the matter with you? 或者What’s wrong with you? 或者What’s the trouble with you? 通过对话的答语得知是询问对方怎么了。因此只有第三项符合题意。故选C
